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Assisted Hatching

When over 35 or IVF Failed

At The Center For Reproductive Health, assisted hatching may be recommended for women who have failed IVF or for women over 35. During the initial stages of development, an embryo is contained in a layer of proteins known as the zona pellucida. To successfully implant into the uterine lining, the embryo must hatch out of the zona pellucida and attach to the walls of the uterus.

Assisted hatching is a lab technique that was developed when it was observed that embryos that had a thin zona pellucida had a higher rate of implantation during In Vitro Fertilization (IVF). Embryologists create a small hole in the outer lining using micromanipulation techniques under a microscope during the fourth day of embryo development.

Assisted hatching helps with IVF success in couples in which the women are over 35 or couples who have had multiple failed IVF cycles. It is thought that some women may fail multiple cycles of IVF because their eggs have a thicker shell, and assisted hatching can help with this problem.

CRH does not use assisted hatching with every patient. Assisted hatching may be indicated for patients with a poor prognosis, such as older patients or those with two or more failed IVF cycles and poor embryo quality. In those patients, there have been higher clinical pregnancy rates and implantation rates after assisted hatching.

There is some risk of monozygotic twins with this process.

Become An Egg Donor

Helping other Women to Achieve their Dream

Women who are interested in egg donation may choose to be a Known or Anonymous donor. If you are interested in becoming an egg donor please click the button below and fill out the application.

Donate Remaining Embryos

Over 25 Years of Success Treating Infertility

Since 1995, we have been an innovator in, IVF, infertility treatment, and genetics care, and have helped thousands of patients worldwide realize their dreams of starting a family.

Adopt Embryos

Why Choose Embryo Adoption

A more private way to adopt

The process of receiving donated embryos is less obvious to the public which allows for more privacy than traditional adoption.

  • Greater degree of privacy
  • Anonymous
  • More control of timing

More convenient than IVF

Some intended parents may choose embryo adoption for its speed and convenience

  • Fewer procedures than IVF
  • No surgical retrieval
  • Fewer medications

More cost-effective

Embryo adoption is a fraction of the cost of traditional adoption and less than the average cost of IVF

  • Lower cost than traditional adoption
  • Lower cost than most IVF options
  • Lower cost medications

Less waiting

The waiting period for embryo adoption can be shorter than that traditional adoption and often quicker than IVF

  • Shorter waiting times
  • Quicker than IVF
  • Fewer clinic visits

Genetic diversity

In some cases, intended parents may wish to have a child who doesn't share their genetic material for medical reasons or personal ones.

  • Avoid passing on a hereditary disease
  • Choice of genetic makeup
  • Increased potential for a healthy baby

High success rates

Compared to IVF with you own eggs and sperm, using donated embryos often has a similar or higher success rate

  • Typically better outcomes

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